| DB ID | MyCo_1685 |
| Title | Evaluation of interleukin-8 levels in the diagnosis of invasive pulmonary aspergillosis in patients with haematological malignancies |
| Year | 2024 |
| PMID | 38592958 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | Haematological malignancies |
| Genus | Aspergillus |
| Species | terreus |
| Organism | Aspergillus terreus |
| Ethical Statement | This study, designed as a prospective case-control study, was conducted with the approval of the Ondokuz Mayıs Uni- versity Clinical Research Ethics Committee on 03.06.2021 and numbered 2021/303. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-8 |
| Biomarker Full Name | Interleukin-8 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Turkiey |
| Cohort | Here conducted this study with 50 controls and 25 IPA patients with haematological malignancies. |
| Cohort No. | 25 Patients and 50 control |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.72 |
| Specificity | 0.64 |
| Positive Predictive Value | 0.5 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive pulmonary aspergillosis (IPA) is common in patients undergoing treatment for acute leukaemia, haematopoietic stem cell or solid organ transplantation, and in patients re- ceiving corticosteroids. In addition, influenza-associated pul- monary aspergillosis (IAPA) and COVID-19-associated pul- monary aspergillosis (CAPA) have been increasingly reporte in recent years. The management of invasive aspergillosis is complicated due to lack of appropriate tools to assess disease progressionandresponsetotreatment. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | Human interleukin-8 ELISA kit (Bioassay Technology Laboratory, Shanghai, China) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
