MycoBiomDB – Record Details (MyCo_1668)

Biomarker Record Details

Database ID: MyCo_1668
DB IDMyCo_1668
TitleCirculating microRNA sequencing revealed miRNome patterns in hematology and oncology patients aiding the prognosis of invasive aspergillosis
Year2021
PMID33735827
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementThis study design and protocol were approved by the Institutional Review Board of the Faculty of Human Medicine, Zagazig University.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameIL-5
Biomarker Full NameInterleukin-5
Biomarker TypeDiagnostic/Prognostic
BiomoleculeProtein
Geographical LocationEgypt
CohortA total of 30 controls, 30 allergic asthmatic patients, 30 severe asthma with fungal sensitization (SAFS) patients, and 30 ABPA patients were included.
Cohort No.90 Patients and 30 Control
Age GroupNone
P Valuep<0.001
Sensitivity0.867
Specificity0.8
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsRayBio® Human IL-5 ELISA Kit according to the manufacturer’s protocol (catalog no.: ELH- IL5; RayBiotech, Parkway, GA, USA).
Assay DataNone
Validation Techniques usedqRT-PCR, ELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone