MycoBiomDB – Record Details (MyCo_1560)

Biomarker Record Details

Database ID: MyCo_1560
DB IDMyCo_1560
TitleBlood Aspergillus RNA is a promising alternative biomarker for invasive aspergillosis
Year2016
PMID27335056
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThe Institutional Review Board (IRB) or Ethics Commit- tee of each institution as described previously approved the prospective study. Evaluation of Aspergillus RNA biomarker was approved by Rutgers Health Sciences IRB.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortThis prospective, noninterventional study conducted at 18 centers across the United States and Belgium has been re- ported recently. a total of 47 patients with proven or probable IA were included in the analysis of correlation between clinical outcome and early changes in serum and BG.
Cohort No.47
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone