| DB ID | MyCo_1542 |
| Title | Clinical value of (1,3)-β-D-glucan, mannan, antimannan IgG and IgM antibodies in diagnosis of invasive candidiasis |
| Year | 2019 |
| PMID | 30820536 |
| Fungal Diseases involved | Invasive candidiasis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The study was approved by local ethics committee. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG + MN |
| Biomarker Full Name | 1-3-beta-D-Glucan + Mannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | This single site retrospective case-control study was performed at PLA General Hospital (Beijing, China) between June 2016 and February 2018. During 2016 to 2018 serum samples from 71 patients with IC and 185 patients without IC were collected. Serum samples from 41 patients with bacteremia were also enrolled as additional control. |
| Cohort No. | 71 Patient and 185 control |
| Age Group | 18-92 |
| P Value | None |
| Sensitivity | 0.859 |
| Specificity | 0.811 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA + Assay |
| Analysis Method | ELISA Based |
| ELISA kits | Plate ELISA kit (Dynamiker Candida Mannan assay, Dynamiker Candida albicans IgG assay and Dynamiker Candida albicans IgM assay, Dynamiker Biotechnology Co., Ltd, China). |
| Assay Data | Dynamiker Fungus (1,3)-β-D-glucan assay (Dynamiker Biotechnology Co., Ltd, China) |
| Validation Techniques used | ELISA, Dynamiker Fungus (1,3)-β-D-glucan assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
