| DB ID | MyCo_1527 |
| Title | Serum C-reactive protein and haptoglobin decrease in the first three months of treatment and relative change in haptoglobin predict remission in dogs with pulmonary coccidioidomycosis |
| Year | 2024 |
| PMID | 38901453 |
| Fungal Diseases involved | Pulmonary coccidioidomycosis |
| Associated Medical Condition | None |
| Genus | Coccidioides |
| Species | spp. |
| Organism | Coccidioides spp. |
| Ethical Statement | The current study, from which the archived samples originated, was conducted in accordance with guidelines for clini-cal studies and approved by the Midwestern Univer- sity Animal Care and Use Committee (protocol No. 3024). Written informed consent was obtained for all included dogs that had archived serum. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Dog |
| Host Scientific name | Canis lupus familiaris |
| Biomarker Name | CRP |
| Biomarker Full Name | C-reactive protein |
| Biomarker Type | Prognostic |
| Biomolecule | Protein |
| Geographical Location | Multi-Location |
| Cohort | 31 client-owned dogs with newly diagnosed pulmonary coccidioidomycosis from October 2020 to February 2021 were included in a retrospective cohort study that utilized archived serum. |
| Cohort No. | 31 |
| Age Group | 38 ± 15.6 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Assay |
| Analysis Method | ELISA Based |
| ELISA kits | The TECO®Canine cCRP assay Kit (TECOmedical group, Sissach,Switzerland) |
| Assay Data | None |
| Validation Techniques used | Canine cCRP assay, High-performance liquid chromatography (HPLC) Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
