| DB ID | MyCo_1504 |
| Title | Role of serum (1,3)-β-d-glucan assay in early diagnosis of invasive fungal infections in a neonatal intensive care unit |
| Year | 2017 |
| PMID | 29144965 |
| Fungal Diseases involved | Invasive fungal infection |
| Associated Medical Condition | Neonatal sepsis |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The Research Ethics Committee of Mansoura Faculty of Medicine approved the study, and written informed consents were obtained from the parents of all neonates included in the study. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Egypt |
| Cohort | A prospective multicenter clinical trial conducted on infants at high risk for invasive fungal infections, with suspected late onset sepsis, admitted to a neonatal intensive care unit at Mansoura University Children’s Hospital and Mansoura General Hospital between March 2014 and February 2016. A total of 77 newborn infants with high risk of invasive fungal infection were classified based on blood culture into three groups: no fungemia (41 neonates with proven bacterial sepsis), suspected fungemia (25 neonates with negative blood culture), and definite fungemia group (11 neonates with culture-proven Candida). |
| Cohort No. | 77 |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.636 |
| Specificity | 0.951 |
| Positive Predictive Value | 0.778 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Dynamiker Fungus analysis |
| ELISA kits | Dynamiker Fungus Kit (Dynamiker Biotechnology, Tianjin, China) |
| Assay Data | None |
| Validation Techniques used | Dynamiker Fungus analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
