MycoBiomDB – Record Details (MyCo_1490)

Biomarker Record Details

Database ID: MyCo_1490
DB IDMyCo_1490
TitleIsolation and identification of Candida species in patients with orogastric cancer: susceptibility to antifungal drugs, attributes of virulence in vitro and immune response phenotype
Year2016
PMID26905729
Fungal Diseases involvedCandida infection
Associated Medical ConditionOrogastric cancer
GenusCandida
Specieskrusei
OrganismCandida krusei
Ethical StatementThis study is approved by the Research Ethics Committee of the University of Vale do Rio Doce (COEP PQ25 / 10-10).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTNF-α
Biomarker Full NameTumor Necrosis Factor alpha
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationBrazil
CohortFifty nine patients with orogastric cancer were selected. Cancer diagnosis was confirmed by histopathology assays, and thirty-four healthy individ- uals were selected for the control group.
Cohort No.59 Patients and 34 controls
Age GroupNone
P Valuep≤0.0001
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodCytometric Bead Array flow citometry assay
ELISA kitsHuman Th1/Th2 cytokine cytometric bead array (CBA) kit (BD PharMingen, San Diego, CA).
Assay DataNone
Validation Techniques usedCytometric Bead Array flow citometry assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone