MycoBiomDB – Record Details (MyCo_1403)

Biomarker Record Details

Database ID: MyCo_1403
DB IDMyCo_1403
TitleProlyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis
Year2013
PMID23356446
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementAll animal research procedures were approved by the Institutional Animal Care and Use Committee at the University of Texas Health Science Center at San Antonio.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupAnimal
Host Common namePig
Host Scientific nameCavia porcellus
Biomarker NamePFP
Biomarker Full NameProlyl endopeptidase Probe - PFP
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortNone
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodComparative protease activity profiling
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA, Platelia Aspergillus; Bio-Rad, Edmonds, WA)
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedComparative protease activity profiling
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone