| DB ID | MyCo_1388 |
| Title | Serum levels of malondialdehyde and 4-hydroxy-2,3-nonenal in patients affected by familial chronic nail candidiasis |
| Year | 2004 |
| PMID | 15693608 |
| Fungal Diseases involved | Familial chronic nail candidiasis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The patients gave their written informed consent, and the study was conducted in accordance with the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | HNE |
| Biomarker Full Name | 4-hydroxy-2,3-nonenal |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Italy |
| Cohort | Seven family members affected by FCNC (3 males, 4 females, with a mean age 29.8 years, range 5 to 48), presenting a Candida-caused ony- comycosis involving all the nails of hands and feet, and with oral and vaginal swabs negative for Candida infection, were enrolled in this study. As control group, 14 healthy donors (HDs), sex and age matched, were also enrolled. |
| Cohort No. | 7 |
| Age Group | May-48 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Chronic mucocutaneous candidiasis (CMC) is a heteroge- neous clinical syndrome and is characterized by chronic infections of the skin, nails, and mucous membranes, caused by organisms of the genus Candida. |
| Technique | Analytic |
| Analysis Method | Colorimetric assay |
| ELISA kits | Colorimetric assay kit (Calbiochem-Novabiochem Corporation (La Jolla, CA, USA)) |
| Assay Data | None |
| Validation Techniques used | Colorimetric assay |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
