MycoBiomDB – Record Details (MyCo_1385)

Biomarker Record Details

Database ID: MyCo_1385
DB IDMyCo_1385
TitleSerum potassium, albumin and vitamin B12 as potential oxidative stress markers of fungal peritonitis
Year2021
PMID34779336
Fungal Diseases involvedFungal peritonitis
Associated Medical ConditionNone
GenusNone
SpeciesNone
OrganismNone
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePotassium
Biomarker Full NamePotassium
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortThis is a single-center and retrospective analysis of all patients suffering FP in the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China between April 2015 and April 2020. A total of 291 episodes of peritonitis were observed between April 2015 and April 2020, including 21 cases of FP.
Cohort No.291
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismFungal peritonitis (FP) remains a serious complication of peritoneal dialysis (PD), with higher morbidity (1–23.8%) and mortality (2–25%) than bacterial PD- related peritonitis (PDRP). Updated guidelines recom- mend effective antifungal therapy and expeditious catheter removal once the diagnosis is established. However, early diagnosis and treatment are often diffi- cult since the clinical manifestations are not specific and microbiological results are belated. Therefore, it is urgent to identify inexpensive, accessible, and sensitive laboratory markers for predicting the disease.
TechniqueAnalytic
Analysis MethodCobas c702 or 801 automatic biochemical analyzers
ELISA kitsNone
Assay DataNone
Validation Techniques usedCobas c702 or 801 automatic biochemical analyzers
Up Regulation Down RegulationDecrease
Sequence DataNone
External LinkNone