MycoBiomDB – Record Details (MyCo_1383)

Biomarker Record Details

Database ID: MyCo_1383
DB IDMyCo_1383
TitleIncidence and risk of vaginal candidiasis associated with sodium-glucose cotransporter 2 inhibitors in real-world practice for women with type 2 diabetes
Year2018
PMID30136398
Fungal Diseases involvedVulvovaginal candidiasis
Associated Medical ConditionType 2 diabetes
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementThe study was approved by the local ethics committee as #251014, and all participants provided written informed con- sent.
Site of InfectionVagina
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceVaginal Fluid
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameSGLT2 inhibitor
Biomarker Full NameSodium–glucose cotransporter 2 (SGLT2) inhibitor
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortThe participants were 114 women with type 2 diabetes who were free of vaginitis symptoms and started SGLT2 inhibitors. Vaginal candidiasis tests through self-administered swabs were carried out at baseline, 6 and 12 months.
Cohort No.114
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodChromoagar-Candida swab analysis
ELISA kitsChromoagar-Candida swab Kit (Kanto Kagaku, Tokyo, Japan)
Assay DataNone
Validation Techniques usedChromoagar-Candida swab analysis
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone