| DB ID | MyCo_1368 |
| Title | Combination of C-Reactive Protein and Procalcitonin in Distinguishing Fungal from Bacterial Infections Early in Immunocompromised Children |
| Year | 2022 |
| PMID | 35740137 |
| Fungal Diseases involved | Invasive fungal infection |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | This study was approved by the Ethics Committee of the first Affiliated Hospital of Sun Yat-sen University in China and complied with the tenets of the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | PCT & CRP |
| Biomarker Full Name | Procalcitonin and C-reactive protein |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | In a retrospective study performed at our department, we analyzed clinical records of hospitalized children with hematology disorders and solid tumors ≤16 years old. Among the 126 patients, 102 (80.9%) were diagnosed with bacterial bloodstream infections and 24 (19.1%) had proven or probable IFI. |
| Cohort No. | 126 |
| Age Group | YYYY-00-DD 00:00:SS |
| P Value | p<0.001 |
| Sensitivity | 0.875 |
| Specificity | 0.873 |
| Positive Predictive Value | 0.882 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Chemiluminescence Immunoassay and Roche cobas e601 analyzer |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Chemiluminescence Immunoassay , Roche cobas e601 analyzer |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
