| DB ID | MyCo_1329 |
| Title | Clinical factors associated with a Candida albicans Germ Tube Antibody positive test in Intensive Care Unit patients |
| Year | 2011 |
| PMID | 21388550 |
| Fungal Diseases involved | Invasive candidiasis |
| Associated Medical Condition | surgical patients admitted in ICU |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | The institutional review boards at each participating institution approved the study and informed consent was obtained in each patient included in the study. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CAGTA |
| Biomarker Full Name | Candida albicans Germ Tube Antibody (CAGTA) |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Spain |
| Cohort | Fifty-three miscellaneous critically ill patients were included in the study, 37.7% of whom needed surgical procedure during their stay in the ICU. |
| Cohort No. | 53 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive candidiasis (IC), especially in the critical care setting, has become an excellent target for prophylactic, empiric, and pre-emptive therapy interventions due to its increased incidence, high morbidity, mortality rate, and associated healthcare costs. Although the past few years have brought exciting developments in anti- fungal pharmacotherapy, the mortality rate remains excessively high. |
| Technique | Immunological assay |
| Analysis Method | CAGTA Immunofluorescence test Kit (Vircell Microbiologist S.L., Granada, Spain) |
| ELISA kits | CAGTA Immunofluorescence test Kit (Vircell Microbiologist S.L., Granada, Spain) |
| Assay Data | None |
| Validation Techniques used | CAGTA Immunofluorescence Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
