| DB ID | MyCo_1311 |
| Title | Accuracy of β-D-glucan for the diagnosis of Pneumocystis jirovecii pneumonia: a meta-analysis |
| Year | 2012 |
| PMID | 22329494 |
| Fungal Diseases involved | Pneumocystis jirovecii pneumonia |
| Associated Medical Condition | None |
| Genus | Pneumocystis |
| Species | jirovecii |
| Organism | Pneumocystis jirovecii |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | BDG data were analysed for 357 PCP cases and 1723 controls. |
| Cohort No. | 357 Patients and 1723 control |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.948 |
| Specificity | 0.863 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Pneumocystis jirovecii pneumonia (PCP) is a common and potentially serious opportunistic infection affecting patients with immunosuppression due to various conditions. Such conditions include infection with human immunodeficiency virus (HIV), as well as haematological malignancies, solid organ transplantation, solid tumours, and treatment with cer-tain immunosuppressive agents [1].Although PCP often has a characteristic clinical presentation with fever, dry cough, dyspnoea, hypoxia and diffuse ground glass opacities in the chest X-ray, the differential diagnosis of pulmonary infiltrates in patients with immunosuppression is broad. |
| Technique | Bioinformatics analysis |
| Analysis Method | Bivariate meta-analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Bivariate meta-analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
