MycoBiomDB – Record Details (MyCo_1185)

Biomarker Record Details

Database ID: MyCo_1185
DB IDMyCo_1185
TitleClinical viability of Fungitell, a new (1→3)-β-D: -glucan measurement kit, for diagnosis of invasive fungal infection, and comparison with other kits available in Japan
Year2011
PMID21210174
Fungal Diseases involvedInvasive fungal infection
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortA total of 121 patients who underwent measurement of plasma b-D-glucan practically between April 23rd and June 4th, 2003 at Kawasaki Medical School Hospital were investigated using stored plasma samples. When multiple plasma samples were available, the sample showing the highest value with the G-MK was evaluated.
Cohort No.121
Age Group15–91
P ValueNone
Sensitivity0.417
Specificity0.968
Positive Predictive Value0.625
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodPlatelia Candida Ag (BioRad, Marnes La Coquette, France), QIAamp DNA kit (QIAGEN, Hilden, Germany)
ELISA kitsPlatelia Candida Ag (BioRad, Marnes La Coquette, France), QIAamp DNA kit (QIAGEN, Hilden, Germany)
Assay DataFDA approved Fungitell assay
Validation Techniques usedBeta-Glucan test Maruha (Maruha)
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone