| DB ID | MyCo_1063 |
| Title | Cholinesterase of rats experimentally infected by Cryptococcus neoformans: Relationship between inflammatory response and pathological findings |
| Year | 2015 |
| PMID | 26376950 |
| Fungal Diseases involved | Cryptococcosis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | The procedure was approved by the Committee on Ethics in Animal Experimen- tation of Universidade Federal de Santa Maria (protocol number 073/2012). |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Animal |
| Host Common name | Rat |
| Host Scientific name | Rattus norvegicus |
| Biomarker Name | BChE |
| Biomarker Full Name | Butyrylcholinesterase (BChE) |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Brazil |
| Cohort | Twenty male Wistar rats (Rattus norvegicus) with 90 days of age and 298 (±29) g of average weight were kept in cages housed in a room with controlled temperature and humidity (25◦C; 70%). |
| Cohort No. | 20 |
| Age Group | None |
| P Value | p<0.05 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | ELISA commercial kits for rat (eBioscience® , San Diego, USA) |
| ELISA kits | ELISA commercial kits for rat (eBioscience® , San Diego, USA) |
| Assay Data | None |
| Validation Techniques used | AChE enzymatic assay, BChE activity assay, ELISA |
| Up Regulation Down Regulation | Decrease |
| Sequence Data | None |
| External Link | None |
