MycoBiomDB – Record Details (MyCo_1062)

Biomarker Record Details

Database ID: MyCo_1062
DB IDMyCo_1062
TitleThe basophil surface marker CD203c identifies Aspergillus species sensitization in patients with cystic fibrosis
Year2015
PMID26388311
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionCystic fibrosis
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementEthical approval was obtained from our institutional review board.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker Namebasophil surface marker CD203c
Biomarker Full NameBasophil surface marker CD203c
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationIreland
CohortHere prospectively recruited 48 patients with CF to the study between October 2012 and October 2014. As control subjects, 11 healthy volunteers without CF were also recruited.
Cohort No.48 Patients and 11 control
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodBasophil activation test
ELISA kitsNone
Assay DataNone
Validation Techniques usedbasophil activation test (BAT)
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone