| DB ID | MyCo_1060 |
| Title | The role of basophil activation test in allergic bronchopulmonary aspergillosis and Aspergillus fumigatus sensitization in cystic fibrosis patients |
| Year | 2016 |
| PMID | 26922860 |
| Fungal Diseases involved | Allergic bronchopulmonary aspergillosis |
| Associated Medical Condition | Cystic fibrosis |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The study was approved by The Ethical Committee of “Aghia Sophia” Children's Hospital and patients or parents for the minors provided their informed consent before enrollment in the study. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CD203c |
| Biomarker Full Name | CD203c |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Greece |
| Cohort | The CF center of “Aghia Sophia” Children's Hospital provides care to more than 400 CF patients. Diagnosis of CF was confirmed by sweat chloride levels (N 60 mmol/L by quantitative pilocarpine iontophoresis) and genotyping. BAT (CD63 and CD203c) was performed in 17 CF patients with ABPA diagnosis, 24 CF patients with AFS and 15 non-AFS CF patients. |
| Cohort No. | 56 |
| Age Group | None |
| P Value | p<0.001 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Fastimmune™ Kit (BD Biosciences, San Jose, California, USA) , Basotest® Kit (Orpegen Pharma, Heidelberg, Germany), Allergenicity Kit (Beckman Coulter Immunotech, Marseille, France) |
| ELISA kits | Fastimmune™ Kit (BD Biosciences, San Jose, California, USA) , Basotest® Kit (Orpegen Pharma, Heidelberg, Germany), Allergenicity Kit (Beckman Coulter Immunotech, Marseille, France) |
| Assay Data | None |
| Validation Techniques used | Basophil activation test |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
