| DB ID | MyCo_1035 |
| Title | Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis |
| Year | 2022 |
| PMID | 35935947 |
| Fungal Diseases involved | Candidemia |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | All mice procedures were approved by the IACUC of The Lundquist Institute at Harbor-UCLA Medical Center, according to the NIH guidelines for animal housing and care. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | anti-Hyr1 |
| Biomarker Full Name | Anti-Hyr1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Ten to 12 week old BALB/c mice (depending upon active or passive vaccination studies) were allowed to mate at a 1:1 ratio of male to female, and pups delivered ~19-21 days post- conception. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Antibody titers analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Antibody titers analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
