Detailed description page of Hmrbase2
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33871 details |
| Primary information | |
|---|---|
| ID | 33871 |
| Uniprot ID | Q3T181 |
| Description | Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) |
| Organism | Bos taurus |
| Txonomy | Bos , Bovinae , Bovidae , Pecora , Ruminantia , Artiodactyla , Laurasiatheria, Boreoeutheria , Eutheria , Theria , Mammalia , Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii, Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata , Chordata , Deuterostomia , Bilateria , Eumetazoa , Metazoa, Opisthokonta , Eukaryota , cellular organisms |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response (By similarity). |
| Length | 349 |
| Molecular Weight | 37689 |
| Reference | NA |
| Hormone | 1351; 1717 |
| PDB ID | NA |