Detailed description page of Hmrbase2
| This page displays user query in tabular form. |
33867 details |
| Primary information | |
|---|---|
| ID | 33867 |
| Uniprot ID | Q03405-1 |
| Description | Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) |
| Organism | Homo sapiens |
| Txonomy | Homo , Homininae , Hominidae , Hominoidea , Catarrhini , Simiiformes , Haplorrhini , Primates , Euarchontoglires, Boreoeutheria , Eutheria , Theria , Mammalia , Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii, Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata , Chordata , Deuterostomia , Bilateria , Eumetazoa , Metazoa, Opisthokonta , Eukaryota , cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Length | 335 |
| Molecular Weight | 36978 |
| Reference | NA |
| Hormone | P00749 |
| PDB ID | NA |