Detailed description page of Hmrbase2
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33851 details |
| Primary information | |
|---|---|
| ID | 33851 |
| Uniprot ID | P14600 |
| Description | Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) |
| Organism | Rattus norvegicus |
| Txonomy | Rattus , Murinae , Muridae , Muroidea , Myomorpha , Rodentia , Glires , Euarchontoglires, Boreoeutheria , Eutheria , Theria , Mammalia , Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii, Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata , Chordata , Deuterostomia , Bilateria , Eumetazoa , Metazoa, Opisthokonta , Eukaryota , cellular organisms |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
| Length | 407 |
| Molecular Weight | 46366 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA |