Detailed description page of Hmrbase2
| This page displays user query in tabular form. |
33814 details |
| Primary information | |
|---|---|
| ID | 33814 |
| Uniprot ID | Q92847-1 |
| Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasing peptide receptor) (GHRP) (Ghrelin receptor) |
| Organism | Homo sapiens |
| Txonomy | Homo , Homininae , Hominidae , Hominoidea , Catarrhini , Simiiformes , Haplorrhini , Primates , Euarchontoglires, Boreoeutheria , Eutheria , Theria , Mammalia , Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii, Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata , Chordata , Deuterostomia , Bilateria , Eumetazoa , Metazoa, Opisthokonta , Eukaryota , cellular organisms |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels |
| Length | 366 |
| Molecular Weight | 41329 |
| Reference | NA |
| Hormone | O00230; Q9UBU3 |
| PDB ID | NA |