| Primary information |
|---|
| ID | 33805 |
| Uniprot ID | P19756 |
| Description | Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into- Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)] |
| Organism | Sus scrofa |
| Txonomy | Sus ; Suidae ; Suina ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | On GH binding; phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2. |
| Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding; couples to; and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
| Length | 638 |
| Molecular Weight | 71145 |
| Reference | 2243805; 8647880 |
| Hormone | NA |
| PDB ID | NA
|