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33803 details
Primary information
ID33803
Uniprot IDO46600
DescriptionGrowth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into- Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
OrganismBos taurus
TxonomyBos ; Bovinae ; Bovidae ; Pecora ; Ruminantia ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationOn GH binding; phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2.
FunctionReceptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding; couples to; and activates the JAK2/STAT5 pathway.
Length634
Molecular Weight70901
Reference2289631; 9710756; 11
HormoneNA
PDB IDNA