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33786 details
Primary information
ID33786
Uniprot IDQ2Q426
DescriptionAdhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312)
OrganismMacaca mulatta
TxonomyMacaca ; Cercopithecinae ; Cercopithecidae ; Cercopithecoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationAutoproteolytically cleaved into 2 subunits; an extracellular alpha subunit and a seven-transmembrane beta subunit.
FunctionCell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis; degranulation and adhesion. In macrophages; promotes the release of inflammatory cytokines; including IL8 and TNF. Signals probably through G-proteins.
Length822
Molecular Weight90787
ReferenceNA
HormoneNA
PDB IDNA