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33730 details
Primary information
ID33730
Uniprot IDQ865E8
DescriptionMelanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)
OrganismPanthera onca
TxonomyPanthera ; Pantherinae ; Felidae ; Feliformia ; Carnivora ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationNA
FunctionReceptor for MSH (alpha; beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis; the production of eumelanin (black/brown) and phaeomelanin (red/yellow); via regulation of cAMP signaling in melanocytes.
Length317
Molecular Weight34722
Reference12620197
HormoneNA
PDB IDNA