Primary information |
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ID | 33638 |
Uniprot ID | O77616 |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R) |
Organism | Canis lupus familiaris |
Txonomy | Canis lupus (species); Canis ; Canidae ; Caniformia ; Carnivora ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | NA |
Function | Receptor for MSH (alpha; beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis; the production of eumelanin (black/brown) and phaeomelanin (red/yellow); via regulation of cAMP signaling in melanocytes. |
Length | 317 |
Molecular Weight | 34984 |
Reference | 10895310 |
Hormone | NA |
PDB ID | NA
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