Detailed description page of Hmrbase2

This page displays user query in tabular form.

33578 details
Primary information
ID33578
Uniprot IDQ9JI97
DescriptionGrowth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into- Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
OrganismCavia porcellus
TxonomyCavia ; Caviidae ; Hystricomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationOn GH binding; phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2.
FunctionReceptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding; couples to; and activates the JAK2/STAT5 pathway.
Length628
Molecular Weight70355
Reference12110920; 10767558
HormoneNA
PDB IDNA