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33573 details
Primary information
ID33573
Uniprot IDQ95179
DescriptionFollicle-stimulating hormone receptor (FSH-R) (Follitropin receptor)
OrganismEquus asinus
TxonomyEquus ; Equidae ; Perissodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationN-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone.
FunctionG protein-coupled receptor for follitropin; the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
Length687
Molecular Weight76938
Reference9195473
HormoneNA
PDB IDNA