| Primary information |
|---|
| ID | 33570 |
| Uniprot ID | Q90812 |
| Description | Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1) |
| Organism | Gallus gallus |
| Txonomy | Gallus ; Phasianinae ; Phasianidae ; Galliformes ; Galloanserae ; Neognathae (infraclass); Aves ; Coelurosauria ; Theropoda ; Saurischia ; Dinosauria ; Archosauria ; Archelosauria ; Sauria ; Sauropsida ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors; such as adenylate cyclase. Promotes the activation of adenylate cyclase; leading to increased intracellular cAMP levels. |
| Length | 420 |
| Molecular Weight | 48600 |
| Reference | 8536612 |
| Hormone | NA |
| PDB ID | NA
|