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33509 details
Primary information
ID33509
Uniprot IDQ9W539
DescriptionHormone receptor 4 (dHR4) (Nuclear receptor subfamily 6 group A member 2)
OrganismDrosophila melanogaster
Txonomymelanogaster subgroup ; melanogaster group ; Sophophora (subgenus); Drosophila ; Drosophilini (tribe); Drosophilinae ; Drosophilidae ; Ephydroidea ; Acalyptratae ; Schizophora ; Cyclorrhapha ; Eremoneura ; Muscomorpha ; Brachycera ; Diptera ; Endopterygota (cohort); Neoptera (infraclass); Pterygota (subclass); Dicondylia ; Insecta ; Hexapoda ; Pancrustacea ; Mandibulata ; Arthropoda ; Panarthropoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular
Subcellular LocationNucleus
Developmental StageNA
SimilarityNA
Post Translational ModificationNA
FunctionCoordinates growth and maturation by mediating endocrine responses to the attainment of critical weight during larval development. Plays a central role in the genetic cascades triggered by the steroid hormone ecdysone at the onset of metamorphosis; acting as both a repressor of the early ecdysone-induced regulatory genes and an inducer of the ftz-f1 midprepupal competence factor.
Length1518
Molecular Weight162655
Reference15935763; 10731132;
HormoneNA
PDB IDNA