| Primary information |
|---|
| ID | 33508 |
| Uniprot ID | Q9UHX3 |
| Description | Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Autoproteolytically cleaved into 2 subunits; an extracellular alpha subunit and a seven-transmembrane beta subunit. |
| Function | Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis; degranulation and adhesion. In macrophages; promotes the release of inflammatory cytokines; including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation |
| Length | 823 |
| Molecular Weight | 90472 |
| Reference | 10903844; 14702039; |
| Hormone | NA |
| PDB ID | NA
|