| Primary information |
|---|
| ID | 33505 |
| Uniprot ID | Q9PVE4 |
| Description | Thyroid hormone receptor beta (TR-beta) (TRb) (Nuclear receptor subfamily 1 group A member 2) (Thyroid hormone receptor beta-1) (TRbeta1) |
| Organism | Danio rerio |
| Txonomy | Danio ; Danioninae ; Danionidae ; Cyprinoidei ; Cypriniformes ; Cypriniphysae ; Otophysi ; Ostariophysi (subcohort); Otomorpha (cohort); Clupeocephala ; Osteoglossocephalai ; Teleostei (infraclass); Neopterygii (subclass); Actinopteri ; Actinopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Nucleus. |
| Developmental Stage | Expressed both maternally and zygotically. Expressed at the 1 cell stage (0 hpf) but disappears by the 2 cell stage. Expressed again from the 16 cell stage onwards. Embryonic expression increases dramatically around the hatching period. High expression then continues until 6 dpf; before declining. |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for the thyroid gland hormone triiodothyronine (T3). Transactivating activity is ligand-dependent; and is repressed in the absence of T3. |
| Length | 395 |
| Molecular Weight | 45155 |
| Reference | 10687864; 23594743; |
| Hormone | NA |
| PDB ID | NA
|