Primary information |
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ID | 33494 |
Uniprot ID | Q8SPP9 |
Description | Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R) |
Organism | Sus scrofa |
Txonomy | Sus ; Suidae ; Suina ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | Glycosylated. |
Function | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2-GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. |
Length | 764 |
Molecular Weight | 86644 |
Reference | 12880144; 11847099 |
Hormone | NA |
PDB ID | NA
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