| Primary information |
|---|
| ID | 33488 |
| Uniprot ID | Q62893 |
| Description | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (C14) (MIS type II receptor) (MISRII) (MRII) |
| Organism | Rattus norvegicus |
| Txonomy | Rattus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Developmental Stage | Expressed in the mesenchymal cells surrounding the Muellerian duct at embryonic days 14; 15; and 16 and in tubular and follicular structures of the fetal gonads. |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | On ligand binding; forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate; then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
| Length | 557 |
| Molecular Weight | 59749 |
| Reference | 8536608; 8119126; 10 |
| Hormone | NA |
| PDB ID | NA
|