Detailed description page of Hmrbase2

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33485 details
Primary information
ID33485
Uniprot IDQ61539
DescriptionSteroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
OrganismMus musculus
TxonomyMus (subgenus); Mus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationNucleus
Developmental StageFound in the extra-embryonic ectoderm at 5.5 dpc; 6 dpc and 6.5 dpc. At 7.5 dpc; is exclusively detected in chorion; and at 8.5 dpc is present only at its free margin. Expression is not detected in the ectoplacental cone at any stage of development; nor is placental expression detected after 8.5 dpc
SimilarityNA
Post Translational ModificationAcetylated by PCAF/KAT2 (in vitro).
FunctionTranscription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcriptional activity
Length433
Molecular Weight48328
Reference8652414; 16141072; 1
HormoneNA
PDB IDNA