Detailed description page of Hmrbase2

This page displays user query in tabular form.

33478 details
Primary information
ID33478
Uniprot IDQ27987
DescriptionThyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
OrganismBos taurus
TxonomyBos ; Bovinae ; Bovidae ; Pecora ; Ruminantia ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationGlycosylated.
FunctionReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2-GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
Length763
Molecular Weight86431
Reference9134497
HormoneNA
PDB IDNA