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33475 details
Primary information
ID33475
Uniprot IDQ24142
DescriptionNuclear hormone receptor HR78 (dHR78) (Nuclear receptor XR78E/F) (Nuclear receptor subfamily 2 group D member 1)
OrganismDrosophila melanogaster
Txonomymelanogaster subgroup ; melanogaster group ; Sophophora (subgenus); Drosophila ; Drosophilini (tribe); Drosophilinae ; Drosophilidae ; Ephydroidea ; Acalyptratae ; Schizophora ; Cyclorrhapha ; Eremoneura ; Muscomorpha ; Brachycera ; Diptera ; Endopterygota (cohort); Neoptera (infraclass); Pterygota (subclass); Dicondylia ; Insecta ; Hexapoda ; Pancrustacea ; Mandibulata ; Arthropoda ; Panarthropoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular
Subcellular LocationNucleus
Developmental StageHighest expression in third instar larvae and prepupae.
SimilarityNA
Post Translational ModificationNA
FunctionBinds to direct repeats of the sequence 5'-AGGTCA-3'. Inhibits the ecdysone response. Plays an essential role in regulating molting of the tracheal cuticle during larval development.
Length601
Molecular Weight65393
Reference7479849; 7479823; 10
HormoneNA
PDB IDNA