Detailed description page of Hmrbase2

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33456 details
Primary information
ID33456
Uniprot IDP91829
DescriptionNuclear hormone receptor family member nhr-69
OrganismCaenorhabditis elegans
TxonomyCaenorhabditis ; Peloderinae ; Rhabditidae ; Rhabditoidea ; Rhabditomorpha ; Rhabditina ; Rhabditida ; Chromadorea ; Nematoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationNucleus
Developmental StageExpressed in 8 dpc intestinal precursor cells in developing embryos; and in intestine throughout development into adulthood.
SimilarityNA
Post Translational ModificationNA
FunctionOrphan nuclear receptor which; in cooperation with R-SMAD daf-8; modulates the Insulin/IGF-1-like signaling (IIS) pathway; perhaps by regulating expression of the potassium channel exp-2; which in turn modulates the secretion of insulin-like peptide daf-28.
Length373
Molecular Weight41778
Reference15983867; 9851916; 2
HormoneNA
PDB IDNA