Detailed description page of Hmrbase2

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33454 details
Primary information
ID33454
Uniprot IDP79194
DescriptionGrowth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into- Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
OrganismMacaca mulatta
TxonomyMacaca ; Cercopithecinae ; Cercopithecidae ; Cercopithecoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationOn GH binding; phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2.
FunctionReceptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding; couples to; and activates the JAK2/STAT5 pathway.
Length638
Molecular Weight71328
Reference9228076
HormoneNA
PDB IDNA