| Primary information |
|---|
| ID | 33452 |
| Uniprot ID | P63058 |
| Description | Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (c-erbA-1) (c-erbA-alpha) |
| Organism | Mus musculus |
| Txonomy | Mus (subgenus); Mus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Nucleus.; [Isoform Alpha-deltaE6]- Cytoplasm. Note=Sequesters isoform Alpha-1 into this compartment. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones; including triiodothyronine and thyroxine. Isoform Alpha-deltaE6 does not bind DNA; inhibits the activity of isoform Alpha-1; and stimulates myoblast differentiation. |
| Length | 492 |
| Molecular Weight | 55023 |
| Reference | 3399404; 2349106; 16 |
| Hormone | NA |
| PDB ID | NA
|