| Primary information |
|---|
| ID | 33451 |
| Uniprot ID | P56495 |
| Description | Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R) |
| Organism | Ovis aries |
| Txonomy | Ovis ; Caprinae ; Bovidae ; Pecora ; Ruminantia ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Glycosylated. |
| Function | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2-GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. |
| Length | 764 |
| Molecular Weight | 86674 |
| Reference | 9299474 |
| Hormone | NA |
| PDB ID | NA
|