Detailed description page of Hmrbase2

This page displays user query in tabular form.

33441 details
Primary information
ID33441
Uniprot IDP47750
DescriptionThyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
OrganismMus musculus
TxonomyMus (subgenus); Mus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationGlycosylated.
FunctionReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2-GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
Length764
Molecular Weight86583
Reference8170469; 16141072; 1
HormoneNA
PDB IDNA