| Primary information |
|---|
| ID | 33432 |
| Uniprot ID | P35379 |
| Description | Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) |
| Organism | Ovis aries |
| Txonomy | Ovis ; Caprinae ; Bovidae ; Pecora ; Ruminantia ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | [Isoform FSH-R1]- Cell membrane; Multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | N-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin; the follicle-stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase |
| Length | 695 |
| Molecular Weight | 78238 |
| Reference | 8394255; 8439338; 93 |
| Hormone | NA |
| PDB ID | NA
|