| Primary information |
|---|
| ID | 33431 |
| Uniprot ID | P35378 |
| Description | Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) |
| Organism | Mus musculus |
| Txonomy | Mus (subgenus); Mus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | N-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin; the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
| Length | 692 |
| Molecular Weight | 77769 |
| Reference | 10330114; 16141072; |
| Hormone | NA |
| PDB ID | NA
|