Primary information |
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ID | 33413 |
Uniprot ID | P20395 |
Description | Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) |
Organism | Rattus norvegicus |
Txonomy | Rattus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | N-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone. |
Function | G protein-coupled receptor for follitropin; the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
Length | 692 |
Molecular Weight | 77681 |
Reference | 2126341; 1738373; 77 |
Hormone | NA |
PDB ID | NA
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