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33413 details
Primary information
ID33413
Uniprot IDP20395
DescriptionFollicle-stimulating hormone receptor (FSH-R) (Follitropin receptor)
OrganismRattus norvegicus
TxonomyRattus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationN-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone.
FunctionG protein-coupled receptor for follitropin; the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
Length692
Molecular Weight77681
Reference2126341; 1738373; 77
HormoneNA
PDB IDNA