Primary information |
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ID | 33390 |
Uniprot ID | O46600 |
Description | Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into- Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)] |
Organism | Bos taurus |
Txonomy | Bos ; Bovinae ; Bovidae ; Pecora ; Ruminantia ; Artiodactyla ; Laurasiatheria ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | On GH binding; phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2. |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding; couples to; and activates the JAK2/STAT5 pathway. |
Length | 634 |
Molecular Weight | 70901 |
Reference | 2289631; 9710756; 11 |
Hormone | NA |
PDB ID | NA
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