| Primary information |
|---|
| ID | 33381 |
| Uniprot ID | G5ED47 |
| Description | High zinc activated nuclear receptor protein (Nuclear hormone receptor family member nhr-33) |
| Organism | Caenorhabditis elegans |
| Txonomy | Caenorhabditis ; Peloderinae ; Rhabditidae ; Rhabditoidea ; Rhabditomorpha ; Rhabditina ; Rhabditida ; Chromadorea ; Nematoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation; which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn; allows for internal zinc levels to be detected and regulated. |
| Length | 413 |
| Molecular Weight | 46736 |
| Reference | 9851916; 28095401 |
| Hormone | NA |
| PDB ID | NA
|