| Primary information |
|---|
| ID | 33306 |
| Uniprot ID | Q93038 |
| Description | Tumor necrosis factor receptor superfamily member 25 (Apo-3) (Apoptosis-inducing receptor AIR) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death receptor 3) (Lymphocyte-as |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | [Isoform 1]- Cell membrane; Single-pass type I membrane protein.; [Isoform 2]- Cell membrane; Single |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. |
| Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
| Length | 417 |
| Molecular Weight | 45385 |
| Reference | 8934525; 8875942; 89 |
| Hormone | NA |
| PDB ID | NA
|